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Post  Admin Fri Apr 11, 2008 12:08 pm

antiviral substances—

18-THE FOLLOWING ARE CYTOTOXIC ALKYLATING AGENTS(
a-cyclophosphamide—
b-mercaptopurine--
c-chlorambucil--
d-fluorouracil--
e-methotrexate-

19-2,3 DIPHOSPHOGLYCERATE
a-is present in higher conc in maternal erythrocytes than fetal erythrocytes--
b-binds more avidly to haemoglobin A than to haemoglobin E—

c-increases the affinity of haemoglobin for oxygen—
d-is a phospholipid
e- is synthesised by the pentose phosphate pathway


18-HYPERKALEMIA IS A CHARACTERSTIC FINDING IN TINDALL
a-primary aldosteronism
b-treatment with Spironolactone-
c-hyperparathyroidism-
d-ACTH secreting tumours of bronchus-
e-renal failure-

19- CONCERNING INHERITABLE DISEASES
A-huntigdon ,s chorea is transmitted by a dominant gene—
b-phenylketonuria is transmitted by a recessive gene—
c-haemophillia ia an autosomal dominant condition--
d- Von Willebrand disease is a sex linked condition—
e-cystic fibrosis is transmitted by an x linked recessive gene--


20-Early blood borne dissemination is a characteristic feature of:
a) carcinoma of the endometrium –
b) osteosarcoma –
c) basal cell carcinoma –
d) carcinoma of the cervix-
e) choriocarcinoma-

21- in tissue pigmentation the following are associated
a-kernicterus and conjugated billirubin
b-addison disease and increased cutaneous melanin
c-melanosis coli and bile pigments-
d—wilson disease and copper deposition in the cornea-
e-corpus leuteum and carotenoids-

22-acquired diverticular disease of the colon
a-is present in at least 15% of Caucasian over the age of 50 years-
b-is due to congenital abnormality of the bowel wall
c-is associated with increased intraluminal pressure—
d-is associated with muscular thickening—
e-may result in intestinal obstruction—

23 stored blood which is to be used for transfusion—
a-kept at -4 degree
b-must be used in 1 week –
c-is tested for compliment content before transfusion --
d-may be used for platelet replacement –
e-contains an acid anticoagulant –


24- in uncomplicated homozygous beta thalasemia there is
a-hypochromasia--
b-a reduction in haemoglobin A—
c-an increase in haemoglobin F—
d- RED CELL SICKLING
e-presence of megaloblasts in bone marrow-


32-The following are capable of cellular regeneration
a)spinal cord
b)liver parenchyma –
c)gut epithelium –
d)kidney ???
e)bone marrow—


33-during the development of female reproductive system
a-primordial germ cells arise in yolk sac--
b-ovarian development is dependent upon oestrogen activity--
c-the paramesonephric duct give rise to the cervix--
d-the greater vestibular glands arise from the urogenital sinus--
e-differentiation of external genitalia is dependent upon ovarian activity--


36- IN CONGENITAL ADRENAL CORTICAL HYPERPLASIA
a-commonest deficiency is C21
b- plasma cortisol conc is raised –
c-there may be excessive secretion of 17 hydroxy progesterone--
d- sodium retension is characterstic –
e-blood catecholamine conc are increased –


37-- SCHISTOSOMA HAEMATOBIUM
a- is a snail –
b- is prevalent in china—
c- infestation may affect the uterine cervix
d- give rise to chronic granulomatous lesions--
e- infestation predisposes to carcinoma—

38- KETONE BODIES
.
a-can be utilised by theadult brain—.
B-Include acetone -
c-are water soluble --
d- are synthesised in skeletal muscles—
e-can be utilised during starvation—


39-IRON IONS
a-diffuse passively into erythropoitic cells-
b-bind to transferin-
c-are taken up by hepatocytes-
d- are necessary for cytochrome synthesis-
e-are absorbed predominantly by the ileum-

40-- --the conjugation of billirubin
a-takes place in hepatocytes-
b-is catalysed by UDP glucuronyl transferase-
c-is inhibited by phenobarbitone-
d-renders it water soluble-
e-is impaired in acute billiary obstruction-

41- in radiotherapy(

a-1Gray is eq to 1joule per kg
b- the skin usually recieve a greater dose of radiation than underlying tissue-
c-the major effect of radiation energy is to damage the cytoplasm of the cell-
d-cells in tissue which are hypoxic are more vulnerable to radiation-
e-radiation induced changes in tissues may take 6 weeks to develop-


-42--osteomalacia is characterised by
a-mineralization of the periostium –
b-deposition of uncalcifiedbone matrix --
c-normal osteobastic activity --
d-increase capillary fragility -
e-normal calcification of bone—


43-progesterone
a-is a C21 compound
b-synthesised by the ovary before ovulation-
c-increases ventilation-
d- raises BMR-
e-binds to corticotrophin –binding globulin-

44-EPIDERMAL GROWTH FACTOR
A- is mitogenic-.
b- synthesis is stimulated by oestradiol-
c-is a steroid molecule-F ...
d- is found in endometrium--
e- binds to receptor on the nuclear membrane-


45-the following are structural aberrations of chromosomes:
a. deletions --
b. inversions—
c. aneuploidy –
d. . polyploidy-
e translocations—

46-- Messenger RNA
a-Synthesis is dependent on RNA polymerase –
b-is an exact copy of sense DNA—
c-Contains exons –
d-Is measured by Western blotting –
e-translation occurs in the nucleus


47-- BETA SYMPATHOMIMETIC DRUGS MAY—
A- caue bronchospasm—
b-reduce frequency of uterine contraction—
c-cause heart block—
d-reduce diastolic blood pressure—

e- increase blood glucose conc

48- The following statistical statements are correct-
a-in the normal distribution,the value of mode is 1.73 times the median –b-in a distribution skew to the right,the mean lies to the left of median-
c-in the series- 2;7;5;2;3;2;5;8, the mode is 2 -
d-student’s ‘t’ test is designed to correct for skew distribution –
e-the chi squared testmay be used when data are not normally distributed--

50-Contraindicated in breast feeding—

A-POPs
B-Bromocriptine-
C-chloroqunine-
d-??
e-warfarine—F

51-Contraindicated with kidney impairment
A-Dopamine -
B-Gentamycine –
C-Cephahexin
D-Cis platin

52- the following are characters of hypoxic cell death:

A-Apoptosis… --
B-Phagocytosis—…
C-Pyknosis… --
D-Poikilocytosis…
E-Release of phospholipids—

52- the following are characters of hypoxic cell death:

A-Apoptosis… --
B-endocytosis
C-Pyknosis… --
D-Poikilocytosis…
E-koliosytosis

prostagladins-
a-lipooxygenase pathway
b-thromboxane causes vasoconstriction
c-increased in the myometruim
d-?
e-?

linear regression:
a-starts from the origin
b-passes thru the mean-
c-values vary
d-ranking is done???

following test r used to compare 2 drugs a and b
a-student t test
b-meta analysis
c-wiloxone paired test
withney u paired test
e?

toxic shock syndrome
associated with the use of tampoons
b-due to toxigenic starinsof strep
c-infrequently reported outside n america
d-a consequence of previous antibioitic therapy
e-confined to seualy active women

the following can regenerate
a-kidneyepitheluim?
b-pheriheral axons-
c-liver parenchyme
d-bone marrow
e-bone

radiation sensitive
a-bone
b-bone marrow
c-epith of gut
d-skin
e-?

Mycobacteruim
a- are alchochol acid fast
b-does not form spores
c-d-a facultative anaerobes
d-responsible for leprosy
e-pathogenic inhumans all strains

the germination of tetanus spores in a wound is inhibited by

a-tissue trauma
b-oxygen
c-inject of toxoid
d-injection of antitoxin
e-removal of devitalised tissue

Aldosterone
a-reduces Na resorption in PCT
b-reduces Na absorption in descen loop of henle
c-Increase Na absortion in DCT
Increase K loss from the tubule
e increases Na absortion in collecting tubules

the following r conclusive evidence of pregnancy in uterine cureetings???? can, t remmber
a-decidua compacta-
b-Arias -stella changes in endometrail glad-
c-spiral arterioles
d-plasma cell infiltration
e chorionic villi

White cell migration from the bld vessels in areas of inflammation involves--- march 1997/2 21
a-call migration between the endothelial cells
b-a pssive loss of fluid bld elements
c-cell migration independeant of endothelial cell motion
d-initail emigration of polymorhs neutrophils
e-more polymorphs than monocytes after 2 day=

the vulva is supplied by
a-ant cutaneu erve of the thigh
b-femoral br/o genito femoral nerve
c-?
d?
e?

glucocorticoids
a-promote hepatic gluconeogenesis
b-suppress uptake of glucose by muscles
c-promote protein break down
d-promote fat reakdown
e-increase glycolysis

halothane(refer sept 1997)42
a-cardic arrythmias
b-explosive mixtures with air
c-liver damage


53- U/S:

A-Pulstile
B-Increase body temp 1 degree after 15 min scanning..
C-High frequency penetrates deeper TISSUE,-
D-Can distinguish between 2 points closer than 0.5 mm
E-Best echoes are produded by beam at right angle to the structures.

54-Disinfectant solutions may become contaminated with:
1-Enterobacter species –
2-Streptococcus species -
3-Escherichia coli -
4-Pseudomonas aeruginosa -
5-Staphyloccus pyogenes-


55-Nitric oxide
a) is synthesised in the endothelium –
b) has a short half life --
c) causes smooth muscle contraction
d) increases during pregnancy -
e) combines with oxygen to produce L-arginine—





Last edited by Shin on Sat Mar 31, 2007 4:43 pm; edited 5 times in total

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mariahafifah
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Posted: Wed Mar 07, 2007 1:20 pm Post subject: 2007 march

--------------------------------------------------------------------------------

good effort by shin
but few question got modifications eg;
nitrous oxide synthesised by macrophages
naloxone antiemitic effect
drugs contraindicated in breast feeding
drugs causing renal impairment
ultasound
mri
statistics quit difficult all definitions
rna
pre implantation diagnosis
for good result one should not wastes time
only past paper and tim chard is worth all others nothing i subscribed on examination which just wasted my revision time better i would have spent on pastpaper revision becuse of that i did silly mistakes in those answers i was knowing rt also
still i cant predict if i check my 4 stems answer some3 stems correct how to calculate because we r not sure about rest



1) FIBRINOGEN
2) HEPATOGLOGIN
3) FERRITIN
4) ...



- predominantly produced by UG system
- is a kind of lukotriene
- is phospholipid





Post subject: which reactant protein will increase in injury



1) FIBRINOGEN
2) HEPATOGLOGIN
3) FERRITIN
4) albumin
5) ?

Brothers

thank you for many questions - i have been much appreciated by this. I am using onexamination dot com and they have many question posted already from this exam - so to use this and your memory is a great help for my revision for the future exam.


Cell cycle
-prophase I and II
-mitosis I and II

Vulva nerve supply

Urinary bladder - lining/embrology

vagina - embrology

Fetal testis

IL I

MCH I

Function of Neutrophil polymorphs

Fetal HbF

PG

Umblical cord - embrology


kindly let me know what questions came from onexamination except preimplantation and 1 mri rest others were majority from past papers./?



prostaglandins
half lifa 30 min f


il1
produced by macrophages


whartons jelly originate from extra embryonic endodem


detrusor muscle is of mesodermal origin


acute phase proteins are transferrin
alfa feto protein

preimplantation diagnosis
possible 2 detect the sex of the embryo
uses pcr 4 chromosomal deletions
can be used 4 detection of single gene disoderes


facial hair causes
testosterone
mestranol
spironolactone

real time bias
length time bias
negative predictive value



hello....among the new subjects taht appear in march 2007

fibrocystic disease of thr breast...in paper 2 , breast anatomy and breast from endocrine function (in paper 1..)...ie 3 qs we about the breast
levator ani its attachnment and its coverings
endometrial carcinoma
adenomyosis
about measuring the arterial blood pressure and its methods
interleukin 2
prenatal implantation genetic diagnosis
menstural cycle in paper 1 and 2

the repeated questions are present in the past paper u can find them but there were many new questions specially in paper

i finally passed part 1 ahahhaha
5 attempts and finally!!! thanks guys!!

i realised a few mcq books were a waste of time especially kaldon shariff

i passed with the past papers & and onexamination.com alone

tim chard helps a little but i would say only 20 %
chamberlain was waste of time as it has too much detail

compilation of onexamination questions are from there too, at a cheaper price instead of subscribing for only limited time period only!
onexamination really ripping of our monney

hi doc XYZ ,,,wt do u mean by (compilation of onexamination questions are from there too, at a cheaper price instead of subscribing for only limited time period only! ) plzzzzzz answer that coz am appearing next march

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